Data Execution Prevention (DEP) is a relatively new feature of both Intel and AMD hardware that is supported beginning with Windows Server 2003 Service Pack 1 and Windows XP Service Pack 2. DEP is a set of related hardware and software features designed to make it more difficult for malicious programs to execute sensitive code in the operating system. DEP is activated automatically when machines with the DEP hardware protection installed are booted in PAE (Physical Address Extension) mode.
Version 2.4.7 of the Performance SeNTry (NTSMF) data collector will not execute if DEP is active. This does not apply to versions after 2.4.7
For details and options, see this Technical Note.